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Prevage is made by Allergan, the same folks that make BOTOX. Allure magazine named Prevage as a Best of Beauty Award Winner.

According to the Prevage MD Company Line:

"PREVAGE® MD protects your skin from environmental stressors known to cause skin aging including UV light, air pollution, ozone, and cigarette smoke.
The antioxidative power of PREVAGE MD anti-aging treatment has been shown to reduce the appearance of fine lines and wrinkles, as well as skin roughness and
dryness, and to even skin tone to restore youthful-looking skin."

According to Dr. Andrew Scheman, MD, an associate professor of clinical dermatology at Northwestern University Medical Center, as quoted in Prevention Magazine:

"Smaller-than-ever molecules make idebenone an agile, streamlined version of its chemical cousin, CoQ10. They can slip readily into dermal cells in the deepest layer of the skin, where they neutralize destructive free radicals."

Both the MD version and the department store version of Prevage contains idebenone (eh-DE-be-known). Idebenone is an antioxidant that has been found to effectively combat the signs of aging brought on by those nasty little factors such as age, sun damage, and smoking (I have two out of the three working against me).

It also has been used in some neurological diseases because of its powerful antioxidant effects. The prescribed formula contains 1.0 percent idebenone, which seems to cause skin irritation and itchiness in some women who have sensitive skin, and the non-prescribed formula contains 0.5 percent.

For four months, I have put on Prevage MD after I washed my face in the morning. I use Retin-A at night, and have for years, so my skin must not be extremely sensitive because I have never experienced skin irritation nor itchiness.

As to whether I have seen a significant difference, to be honest, I am not sure. I have always used some type of antioxidant, as well as Retin-A for two decades. Rhytiphobia is not something I suffer from because I realize there is only so much preventive maintenance a girl can do. So until beauty scientists come up with a stronger antioxidant for the skin -- maybe CoffeeBerry -- I will continue using Prevage MD.

Prevage Antiaging Night Cream
I've been using Prevage ($125) for the last week. Prevage is a prescription antiaging treatment developed by Allergan, the company that makes Botox. Elizabeth Arden has created a nonprescription variety of Prevage and put it into a night cream. Like the original version, it contains idebenone, a topical antioxidant that's much smaller and therefore better at penetrating the skin. It also contains Mega Complex-A, a blend of antioxidants such as vitamins A and E.

To find out whether this $125 cream delivers, read more

(Full disclosure: Elizabeth Arden's publicity department sent a jar for me to review. I will always tell you whenever a PR firm gives me a product for review that costs more than $100. Transparency and all that.)

I don't really have any wrinkles yet (ahem, sunblock), but I can say is that in the last week, my skin has been doing some great things. The redness in my cheeks has gone down — way down. My skin looks smooth and evenly toned now, and I've been wearing concealer only under my eyes and on my hormonal chin zits. No more redness! I've also found that my T-zone isn't as oily, which is great. I keep looking in the mirror to marvel at the changes that have happened in such a short amount of time.

Plus, I love the dispenser. You just press gently on the button and a bit of lotion plops out. (I don't care if it's gimmicky. I just like it, okay?)

So, is Prevage night cream worth $125? Oh, man. I don't know what to say. I think $125 for a night cream is definitely expensive. No two ways around that! And yet . . . this is the first over-the-counter cream that I would actually consider paying $125 for. Let's face it: Most night creams will moisturize your skin, and some will deliver results, but this is the first one that has done both in a very small amount of time. So, if it's in your budget, try it out. I'm going to go gaze at my skin now.

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